ChAT Displaced Amacrine

References

• Postsynaptic connections (Input)

• Presynaptic connections (Output)
  • ChAT-positive amacrine (non-displaced or displaced) cells contact Off Parasol Ganglion Cells- Jacoby and Marshak ARVO '96

• Function

• Morphology
  • soma is in the GCL
  • Bistratified dendrites in S2 (20% depth) and ~S4 (49% depth) of the IPL Vaney '90 cites Pourcho and Osman, 1986

• Array characteristics - Vaney '90
  • maximum density for both displaced and nondisplaced: 2000-2600 cells/mm2 - this maximum is located where the ganglion cells are stacked 2 deep
  • minimum density for both displaced and nondisplaced: 100 cells/mm2
  • This displaced cell comprises ~65% of the cholinergic amacrines

• Compartmental Model Characteristics

• Location
  • soma is in the INL
  • Bistratified dendrites in S2 and ~S4 of the IPL

• Subclasses

• Synapse types

• Synapse Receptors

• Neurotransmitters
  • synthesize acetylcholine
  • takes up 3H-choline (Masland and Mills '79 as cited by Vaney, Peichl and Boycott (1988))

• Immunoreactivity
  • ChAT (Choline-acetyl-transferase) stains

• Nomenclature
  • equated to the Cb by Vaney, Peichl and Boycott (1988)

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