A22 Amacrine

References

• Postsynaptic connections (Input)

• Presynaptic connections (Output)

• Function
  • Kolb, Nelson and Mariani (1981)
    • Called an "On"-lamina morphological counterpart to the A19 (which has dendrites in the "Off"-lamina of the IPL.)
  • Freed, Pflug, Kolb and Nelson (1996) - note these results are based on the response of 4 A19's and only 1 A22
    • On-Off amacrine - "respond with transient depolarizations to both the onset and the offset of a flashing light"
    • Two spike-like event sizes
    • Narrow dynamic range
    • receptive field is larger than dendritic field: a light bar eleicted a response from a cell when the bar was "separated from the dendritic arbor by 300 um".
    • "Recordings from the single ON-OFF amacrine cell (cell 3) that ramified mostly in sublamina b demonstrated only that it had an ON-OFF response."

• Morphology
  • Kolb, Nelson and Mariani (1981)
    • 12-15 um soma which are large and flattened
    • unistratified
    • dendrites have several varicosities and spines

• Array characteristics

• Compartmental Model Characteristics

• Location
  • Kolb, Nelson and Mariani (1981)
    • stratified only in strata 4 of the IPL (Kolb, Nelson and Mariani, 1981)
    • somas were found in GCL and in the neuropil of the IPL.

• Subclasses

• Synapse types

• Synapse Receptors

• Neurotransmitters

• Immunoreactivity

• Nomenclature
  • Originated in Kolb, Nelson and Mariani, 1981

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